It is similar to Knockout. However, Knockout is hard to manage because you have to invent architecture on your own while jsblocks offers MVC out of the box. Additionally, Knockout don't have routing, server-side rendering, animations, filtering, sorting, paging, lazy loading of views, validation, working with remote data out of the box.

Also the debugging experience is a cool feature - http://jsblocks.com/learn/introduction-why-jsblocks#debuggin....