Not really. The usual guidelines are "have a portfolio of some sort" - IOW, something you can use to demonstrate what you know instead of just leaning on a sad list of keywords. That can be a nice SO profile, but could also be a solid open source project or well-written blog.
If you do plan on showing off your SO profile, don't get hung up on rep - well-written answers that demonstrate mastery of a subject are a lot more useful than an arbitrary number.
If you do plan on showing off your SO profile, don't get hung up on rep - well-written answers that demonstrate mastery of a subject are a lot more useful than an arbitrary number.