Possibly. However evolution's been on that for a good long time -- about 3 billion years.
Where humans have succeeded in enhancing certain areas of biological productivity, it's generally come at a cost in other areas, particularly general robustness.
Another possibility would be to come up with an energy cycle _other_ than ATP, though that would be equivalent to coming up with an independent biological foundation, something you might want to think over at length.
The last time something akin to a new energy cycle happened on earth was when cyanobacteria produced so much free oxygen it accumulated in the atmosphere [0]. This caused a global extinction event and one of the longest ice ages that the planet has known. So yes, we would need to be very careful playing with non-ATP energy cycles...
Could we in principle use some genetic engineering to make this process more efficient?