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Whether you make your site fully screen-reader compatible is up to you, but enabling some simple hacks (e.g. custom stylesheets, browser zooming) really goes a long way.
Yes! It isn't as if "please don't use horrible fonts; please choose high contrast colours; please allow zooming" is some onerous difficult to follow arcane ruleset.
Yes! It isn't as if "please don't use horrible fonts; please choose high contrast colours; please allow zooming" is some onerous difficult to follow arcane ruleset.