My guess is that people in Colorado tend to be more libertarian. They don't want government interference, and at the same time they don't follow the religious culture in the deep south.
There's a little bit of libertarian undercurrent there, but I believe it's more of an emergent phenomenon from the mixing of independent-by-nature left- and right-wing voters. Colorado, with large swaths of rural areas as well as big cities, is rather purple.
Put together left- and right-wing voters, and you get either statism or libertarianism, and Colorado leans towards libertarianism. Or so my theory goes.
IMO both Colorado's right-leaning and left-leaning populations have had a libertarian bent for a long time -- from the "leave us alone" ranchers of Idalia to the "let us be" hippies of Nederland.
My guess is that people in Colorado tend to be more libertarian. They don't want government interference, and at the same time they don't follow the religious culture in the deep south.