this depends entirely on what the nanoparticles are composed of.
gold nanoparticles and carbon nanotubes are materials known as being very active and toxic in certain living systems, and the sort of thing that you describe as having very little research.
metal oxide nanoparticles (entirely likely in a superhydrophobic/oleophobic product) on the other hand, we have ample, ample research on, because volcanoes have been spewing them out of millions of years and we've been breathing them in.
gold nanoparticles and carbon nanotubes are materials known as being very active and toxic in certain living systems, and the sort of thing that you describe as having very little research.
metal oxide nanoparticles (entirely likely in a superhydrophobic/oleophobic product) on the other hand, we have ample, ample research on, because volcanoes have been spewing them out of millions of years and we've been breathing them in.