I had a very similar experience. I know and respect people for whom remote work is a good fit. I'm glad they are able to take advantage of it, and support that option for them. But for me, after about a year of it, I was starting to have real emotional problems, which I've never really had before in my life. The isolation just took a tole on me. Perhaps I wasn't doing it right. Regardless, my new job, a twenty minute bike ride from my house, is, even two years in, still fantastic.