You get lot more data when running real world experiments .
For off world missions, the best examples are the Soviet Venus missions of how iterating and sticking with the goals helped do some incredible research which would be hard to replicate even today .
The benefit of not doing quick and dirty is why we got out The longevity of voyager or some of the mars rovers or ingenuity.
They were "launching cities" as one of their program chiefs said. Yes, when you can arbitrarily tax you population you can afford these loud propaganda headlines.
For launch perhaps, but what about for Moon and/or especially Mars landing?
With limited Mars launch windows, probably faster to have less attempts with more modelling, than vice versa