A lot of P. O. Boxes have their own zip+4 address. You can spot these because the P.O. Box number and the +4 are usually the same (or occasionally the P.O. Box number is the last two digits of the five-digit zip code combined with the +4 so that a piece of mail with a box number and no zip code can be delivered to the correct post office in a large city).
There’s a less-known 11-digit zip code which is unique for every delivery point (so down to the individual residence). I’m not sure if multiple apartments in the same building have distinct 11-digit zip codes, but this does imply that a zip+4 cannot have more than 100 delivery points within its bounds.
Apartments will commonly have multiple Zip + 4 for the building so I imagine each apartment gets unique Zip 11.
Open Google Maps, go to Central Park in NYC, search for apartments and randomly pick one. Then go USPS Zip Code lookup (https://tools.usps.com/zip-code-lookup.htm) and punch in the address leaving off any apartment number so it will show all available addresses. I used 225 E 63rd St New York, NY. Appears they have 8 Zip + 4 assigned to the complex.
I tried again with building in Philly and same story. Each floor of 16 apartments got its own Zip + 4.
