There may be places out there to find reliable information on the efficacy and safety of prescription medication taken off-label, but a guest post from a seller of them certainly is not one.
Actually the good news is that it should actually be easier to find research on these drugs than your standard drugs because they're not being tested by big pharma, which means there should be much less of a file drawer effect.
That said, you'd have to be kind of dumb to think that you can improve your brain function by taking the same cocktail of drugs every day. Taking low doses of different stuff on an intermittent basis, maybe, but hammering the same receptors day in and day out and expecting some sort of longterm benefit is extremely naive.
There are a number of different possible answers to that question. One answer is that it doesn't, it just feels like it does. And if you look at studies of people who are caffeine dependent, they're not actually are more alert after drinking a cup of coffee than people who aren't caffeine dependent and don't drink coffee.
The other answer is that if you're using caffeine from plants then you're getting a different dose each day, and if you're not taking a lot and you're not doing it every day then tolerance will be less of an issue. Also, caffeine breaks down into multiple separate drugs when digested so that may also have some impact on tolerance.
Unfortunately, companies are not legally allowed to discuss or mention in their marketing materials the "Nootropic" effects of these substances due to the FDA. This pushes a lot of the reliable information regarding Nootropics into forums and other areas on the internet. It is pretty interesting to see the communities that thrive around Nootropics. Just trying to learn the basics and build a stack, I have spent hundreds of hours researching.
