I have tried (stopped a couple months ago). The Python extensions broke all the time while they manually patched around the latest MS release a few days later. Syntax highlighting glitched every other day requiring a full reload. Remote dev via SSH or tunnels also randomly stopped working. Liveshare... Essentially they do not own the platform their core product is built on.

Maybe it's fine if you only do local development in other languages (Javascript?), but I completely swore it off.