The probability/impossibility doesn't matter. If we are in a simulation, then there is a chance (no matter how small) the simulation would reward us for acknowledging it when the simulation ends (NG+) or punish us if we don't (your save is deleted). That outcome is a potentially huge upside/downside risk! Compared to the relatively small cost of wrong belief here and now, it's obvious you should assert we do live in a simulation.
Just pointing out that that is the case for Christianity too (not religion in general because others that I am aware of require some sort of actions be taken, although some would say that true acceptance necessarily leads to actions so there is room for debate there). Also, if the creator of the simulation did want to guide us in a specific direction, might they send avatars into the simulation with messages, rather than simply banking on individuals like yourself to come up with the “goal” on their own? I’m not coyly suggesting you must convert, just raising some thoughts that I’ve had.
Christianity requires action from a person to reach metanoia (commonly referred to as repentance), not just belief. Surface level 'I repent' is not what Christianity pushes people to explore but consistent reflecting on yourself/your actions. Christianity recognizes that you need to give people the ability to start (or start back up) at any time which often gets used as an excuse to wait to start until right before you die instead of the intended 'it is never too late to try/to start trying again'.
"Huitzilopochtli might exist, and will punish those who do not sacrifice the hearts of defeated opponents, so I should kill my neighbor and offer his heart."