This is a real "daddy or chips" question, because they all do completely different things. Blender possibly best in terms of "compared to an expensive commercial product". Ghidra is incredibly powerful but has a weird look and feel. Linux is undoubtedly the most influential of those three, but if it had never been invented perhaps we'd be using a BSD instead?
"Best" in terms of "achievement by a single programmer (almost)" is Fabrice Bellard's ffmpeg and QEMU.
"Best" in terms of "achievement by a single programmer (almost)" is Fabrice Bellard's ffmpeg and QEMU.