Is there a huge difference in outcomes, really? On average, I feel like the people who live in dead-end cities and towns that have no hope left in them would move on their own, given the money. But the places that still have promise in the form of natural resources or manufacturing capacity could get their economies restarted, letting them attract people and investment.
Rip people away from the only concept of support they have: Family. Unless your plan includes the ability to move generations of families, you aren't helping people, you are just keeping them impoverished and separated.
Could we make it easier for people to migrate from WV?