NextDNS has not updated its client applications on multiple platforms (iOS/iPadOS/macOS) for several years. Those client applications did have the ability to stop the blocking (or not), but now it's just a toggle that does nothing.
Most of the time when I visit test.nextdns.io it shows as "unconfigured" even though the NextDNS client is installed and configured with a NextDNS profile (and approved in Settings as a VPN provider on these OSes). Sometimes it will work on its own.
I wouldn't recommend NextDNS unless the user is comfortable installing a (somewhat) permanent Profile on these devices with no temporary "off" switch to stop blocking. For me it's important to stop the blocking once in a while.
At least on macOS, there's Little Snitch (paid application), which can subscribe to the same blocklists used by ad blockers and has a working toggle.
They do let you switch it off, it's just a bit buggy sometimes (like having to toggle twice), I know because I use it all the time. https://i.imgur.com/YpSkS93.png
FWIW, in my years of using NextDNS I think I've needed to do this only twice. On Macs, the menubar app lets you enable/disable NextDNS. The average HN reader can probably automate switching to a non-blocking profile for a given length of time. https://community.home-assistant.io/t/nextdns-integration-te...