You deploy complex proprietary heuristics to identify whether incoming requests look more like an attack or more like something a user would legitimately send. If you find a new heuristic and try to deploy it, you'll immediately notice if it throws a bunch of false positives for Chrome, but you might not notice so quickly for Pale Moon or other non-mainstream browsers.
(And if I were doing this on my own, rather than trusting Cloudflare to do it, I would almost surely decide that I don't care enough about Pale Moon users to fix an otherwise good rule that's blocking them as a side effect.)