The sequence (reverse complemented) matches positions 2751-2733 of sequence ID 11652 attached to the patent: https://seqdata.uspto.gov/seqdetail?docId=US09587003B2&publi... - as the other person said, it's located in the S1/S2 furin cleavage site, and produces no BLAST hits outside the SARS-CoV-2 lineage.
It's not entirely clear to me when the sequence was incorporated into the patent - it doesn't look like it was in the first revision. But it looks like it was added before 2020.
The whole theory still has gaps (even if we assume someone was searching specifically within that patent, what would a screen look like to single out that sequence? It would have to be very high throughput and use very sophisticated modeling), but it's interesting.
no screen necessary. you create a bunch of dnas by robot building from scratch every FCS known to man. the "screen" is "this is the guy that hapoened jump out of the test tube and cause a pandemic". more of a selection than a screen i guess
The article: https://www.frontiersin.org/journals/virology/articles/10.33...
The sequence (reverse complemented) matches positions 2751-2733 of sequence ID 11652 attached to the patent: https://seqdata.uspto.gov/seqdetail?docId=US09587003B2&publi... - as the other person said, it's located in the S1/S2 furin cleavage site, and produces no BLAST hits outside the SARS-CoV-2 lineage.
It's not entirely clear to me when the sequence was incorporated into the patent - it doesn't look like it was in the first revision. But it looks like it was added before 2020.
The whole theory still has gaps (even if we assume someone was searching specifically within that patent, what would a screen look like to single out that sequence? It would have to be very high throughput and use very sophisticated modeling), but it's interesting.