I have, many times in the last 2 or 3 years... I still do... It's cheap and easy to implement, it's easy to use and it ads just as much cruft as I'm willing to tolerate. I build boring software, average CRUD applications for government departments, people in this line of work don't give a shit about millisecond delays or reactivity, hell, they don't even care about responsiveness... jQuery facilitates high speed development, provides neat functionality that doesn't get in the way, it's easy to maintain, and keeps people happy.
Even if you did give a shit about those things, all that can be achieved with jQuery. IMO the real downside of jQuery is not being as opinionated as other mentioned "technologies", which leaves too much room for thinking
