Looking at it holistically is precisely what makes it good for humans.
Most activities that change the land from its original state are not done for the long term good of humanity, but for short term profit, which is what finances the activity.
They might try to root out an invasive creature, or a disease causing bacteria, but would they root out themselves?
Most likely they'd change their ways and not be so bad for the land. Humans are a smart and very adaptable species. I'm sure we can master that art.
Looking at it holistically is precisely what makes it good for humans.
Most activities that change the land from its original state are not done for the long term good of humanity, but for short term profit, which is what finances the activity.