From my understanding trpc is very similar, however, the rpc mechanism is not a standard. ts-rest produces openapi schemas and speaks REST over http, as well as a typed client.

That being said, I am actually slowly migrating off ts-rest and adopting @effect/schema and @effect/platform/HttpApi, I foresee this being the direction the typescript ecosystem heads in over the next few years. However, the APIs are not stable yet and it has a bit of a learning curve, so would not adopt lightly