I don’t think it would have much of an impact. And I hate those forced wizards and tutorials as I use excel in lots of environments.
I remember Excel team writing about why they didn’t have advanced settings to turn it off. I don’t remember the rationale but I’d rather have some switches I can set for the situations where I don’t want it.
Although I do want it on and just check my data types. And for the most part I solved this by opening and never editing in Excel. It seems to be the one hack I’ve gotten coworkers to stick with is “don’t click save” when opening large files in Excel.