Many performers use a semi-permanent patch. You effectively build a synthesizer with exactly the affordances you want, and carry the thing to the gig patched up. (Those setups tend to focus a lot of cable management too, lol, so that you can actually reach the controls)
Or, some do improvised live patching, in which the goal is NOT to replicate sounds.
Or, some do improvised live patching, in which the goal is NOT to replicate sounds.