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> the cost to society from alcoholism and obesity

To put that into perspective, annual cost of diabetes to America is $1,200 per capita ($1,300 adjusted for inflation [2]. 40% more than a month of Ozempic [3].

One twelfth of Americans have diabetes [4]. If the government could negotiate just a 10% bulk discount, the payback period on buying every American with diabetes Ozempic would be around a year. Even if everyone ceased treatment after that, even if you only did this for a couple years, we'd see a permanent boost in productivity and health across the American population.

[1] https://pubmed.ncbi.nlm.nih.gov/37909353/

[2] https://www.usinflationcalculator.com

[3] https://ro.co/weight-loss/ozempic-cost-without-insurance/

[4] https://www.niddk.nih.gov/health-information/health-statisti...



Government could build their own plants, these drugs are not under patent, just the drug+delivery mechanism is. This says $5 per month as actual costs.

https://www.healthline.com/health-news/how-affordable-could-...


> these drugs are not under patent

"Semaglutide is expected to become patent-free in the United States no earlier than December 2031" [1].

We could probably strike a volume deal for ~$200 for 5 years and then $75 (the upper end of your study’s estimate for manufacturing cost) for another 5.

[1] https://www.drugpatentwatch.com/p/tradename/OZEMPIC


https://www.cnbc.com/2024/04/30/ftc-challenges-patents-held-...

My understanding is that they are patentening the drug+device and or the dosing, not the molecule. Looks like the FTC is clamping down on it.




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