Yes, it has a bigger more active community with more features and plugins. I used to use screen all the time but then converted to tmux because of modern features that screen didn't support, at that time at least, like displaying certain Unicode characters and a way to restore a previous session. It was a bit of a hassle to make tmux work similar to screen and some things you have to really do in a different way, but overall I'm happy with the switch.

I can only speak from personal experience but I never got deeper into screen than running basic commands in a detached screen and re-attaching it.

But with tmux the docs and ui were just so intuitive that I was a power user within weeks.

Only problem ever was the metacharacter Control-A. We didnt like it, because it messed the workflow in Emacs and Bash.