Dreamweaver, Frontpage, and a dozen other random tools I've used that proclaim to reduce the code associated with design are that way --->. Let us know if you find anything that works for anything non-trivial. Or anything trivial for that matter.
http://scrollkit.com! very flexible in terms of design, though not made for liquid layouts. (disclosure: my project) let me know if there's anything you want it to do that it doesn't.
