Except, you always interact with computerS no matter what provider or architecture you use. It's inescapable as long as you're doing business in software. The trade-offs in architecture and regionality do NOT go away just because a company abstracts over it. They may be able to set up read replicas and consensus on the fly and be able to detect when various approaches make the most sense, but you are still at the mercy of the accompanying constraints. For most use cases, none of this may matter. When you do run into a use case where it matters, you should be fully aware of what trade-offs you're making and have control over them.

Not to mention, regions matter when you're serious. GDPR/DSA/DMA/India/China -- the list goes on. Certain data must live in certain bubbles.