I flip between Flask and Django depending on what I'm doing.

If I want to make something "from scratch" I do it with Flask, if I've got an existing database (or something that can be wrangled into a database) I do it in Django.

I’m mostly hacking together APIs, but may do a Django project sooner or later. Though I personally deplore ORMs.

You don't have to use the ORM, but if you do you get a lot of cool stuff "for free".

Also it's one of the better ORMs, a lot of people were put off by the fairly broken implementation in early RoR.