"an immune system controller found in 'barrier tissues' such as the intestine"
This sounds like academic wording for "leaky gut."
"doing so had a dramatic effect on the production of bile acids and other metabolites in the microbiomes of lab mice. With this receptor out of commission, inflammation decreased and the mice recovered."
Who might have guessed MS could be caused by an imbalance in a bile humor? Physicians from antiquity.
Leaky gut is a real medical term, but one that unfortunately has been picked up by the woo/toxin/alternative medicine crowd. Some researchers use the term intestinal permeability instead.
Both terms refer to barrier dysfunction in the tight junctions that make up the cell wall of the intestines. By becoming more permeable, the gut wall lets bacteria through and allows them to either colonize the surrounding tissue and/or enter the blood stream, a phenomenon known as bacterial translocation. Patients with intestinal permeability may have detectable levels of bacteria in their blood. A healthy gut absorbs nutrients and water through the gut wall, but protects the body against pathogens.
Studies show that some autoimmune conditions like psoriasis and Crohn's are associated with increased intestinal permeability. Unfortunately, "leaky gut syndrome" took this idea and ran with it, and as a result we have a lot of snake oil going around.
As for this paper, the connection is really interesting, and seems to fill in some gaps. For example, one of the newest medications for psoriasis, Vtama, is an aryl hydrocarbon receptor agonist. Psoriasis has also been successfully treated with bile acids in at least two studies.
Just a slightly high ferritin measure. The concern was that I was already a very frequent donor (platelets, which you can donate more often), and if I stopped it could potentially be really bad.
But it was nothing. Just a slightly off scale number, unusual but not dangerous.
Dr Terry Wahls isn't going off of research. She wanted to sell books - and has. She's commonly known as a fraud/snake oil salesmen to all but the folks that buy into her scam.
I have no issue with folks telling others to eat more vegetables and otherwise have a generally healthy diet.
I do have an issue with telling folks to eat a specific style of diet, which is difficult to maintain, especially with the promise that it'll cure a disease, one that leaves some folks with little hope. There is no quality research proving her right.
"an immune system controller found in 'barrier tissues' such as the intestine"
This sounds like academic wording for "leaky gut."
"doing so had a dramatic effect on the production of bile acids and other metabolites in the microbiomes of lab mice. With this receptor out of commission, inflammation decreased and the mice recovered."
Who might have guessed MS could be caused by an imbalance in a bile humor? Physicians from antiquity.