That's what I did in Sciter:

1. Added element.$("selector") and element.$$("selector") functions. Later one allows to work with JQ sets:

     for(let el of parent.$$(".child"))
        ...

2. Added element.on("eventname" [,"selector"], handler) and element.off()

These two allow to reduce need for JQuery to almost zero.

Also added JSX as a built-in feature to JS/runtime. So,

     function Child(props) {
        return <p>Generated child {props.index}</p>;
     }

     function Main() {
        const list = [1,2,3];
        return <main>
          { list.map( el => <Child index={el} /> ) }
        </main>
     } 

     // add the list to the DOM:
     document.body.append(<Main />); 

These three simple things, together with elment.patch(...JSX...) eliminate need for as JQuery as ReactJS almost completely.