Would you mind citing a case of harm caused by pharmacological effects of mushroom overdose? My own online research since your post found no such recorded instances, but perhaps we're using different terminology.
Its hard to find serious papers about it because most of the time its due to "abuse" of drugs and (!) mixed consums.
Anyways, I had a friend who was really into mushrooms overall (not only psychoactive ones) and while he was pretty open to drug using he stated multiple times that overdosing can lead to bad trips and so called "hängenbleiben" (I dont now the english term, it means the trip never really stops).