As a high school student, I had all sorts of interests: Math, science, electronics, music, computers. GEB reinforced my interest in math as being more than just useful (for physics and electronics), and led me to choose math as my college major. Not surprisingly, getting interested in math as an end unto itself was what got me good enough at it, to actually make it useful for those other things, and I ended up doing my graduate work in physics.
+1, Same here. Like, I'm not even happy about it, I could have done something very different if i didn't read that book. "It blew my mind at an impressionable age" is a comment I read online about this book, very accurate!