It’s basically a giant inside joke. Explaining it won’t do any good, not helped by the fact that in a lot of cases with ironic and absurdist humor, it’s not really funny on its own premise.
The meme basically took the phrase “Don’t lecture me with your thirty dollar haircut” and stuck it next to a bunch of emoji. For some reason, this transformed into videos where the emoji was interpreted as memetic audio clips. In some cases, I’ll admit the joke just boils down to “loud stupid noise funny.” But the reason why people find it funny, is literally because they know it’s not. You’ll even see them saying things like, “I know this isn’t funny, but I can’t stop laughing.” If anyone understands enough psychology to explain WTF is going on here, I’d love to know.
On the other hand, the meme, which is admittedly not really funny on its own, spiraled into a fairly neat website where you can actually sequence music, sort of like Mario Paint. I think that’s it’s neat regardless of what you think of the humor that lead to it.
The original line, the meme after that, or this website?
The line is silly and strongly acted, I think it's easy to see why it's funny.
Then sharing it around and tossing some emojis and sound effects on isn't a huge improvement but whatever it's entertaining to throw some images and sounds onto things.
And it should be easy to see why this website is popular just as a music tool, with the line not very important and largely there to put things in a silly mood. Some people will find it funny and some won't, but there doesn't need to be anything funny about the website for it to be fun.
Edit: you have a long history of breaking the site guidelines. We've asked you many times to stop, but you've continued. You did it here just recently: https://news.ycombinator.com/item?id=30096800. If you don't stop this, we're going to have to ban you. I don't want to ban you, so please stop this.