"More than 95% of human anti-pig antibodies are directed against 3 pig carbohydrates: Gal 1 to 3αGal (≈80%–90%), Neu5Gc (≈5%–15%), and β4Gal (1%–5%)"
"To reduce anti-pig antibody binding to the xenograft, the 3 principal carbohydrate antigen targets have each been successfully removed from pigs by gene knockout (KO) (Figure 3)"
