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Assuming that Denmark vaccinated oldest/most vulnerable first, this could be a confounded estimate (because age both means you got the vaccine first, and that your immune system will be less effective against Covid).

Personally, I think it's a statistical fluke, and was going to argue that it must be due to a smaller sample size until I saw the width of the confidence intervals (CI's get narrower as observations increase).

Very odd, and I'll be surprised if that makes it through peer review intact.



It's a statistical fluke that has been observed with Delta as well, particularly with the AstraZeneca vaccine:

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3949410

It stands to reason that the unvaccinated at this point are in large parts hermits who are "protected" by their lifestyle. However, it's also plausible that the non-neutralizing antibodies from the vaccine induce a suboptimal immune response with Omikron.




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