Though say for argument's sake you just want to reduce road deaths in total. Wikipedia has the annual world total at 1,350,000. Tesladeaths.com had confirmed Tesla autopilot deaths for 2021 at 10. On that basis you might want to crack ahead with developing self driving to bring the 1.3m figure down at some point.
Those numbers aren’t remotely comparable. Airline autopilot deaths are tiny compared to human pilots, but they do different jobs and are available in different kinds of planes flown by different kinds of pilots in different situations, so you really can’t compare auto-pilot miles to non-autopilot miles by just comparing deaths per mile.
In Germany 2,719 people died in traffic in 2020. In the US it was around 40,000. Germany has 1/4 the population, so maybe there are many other factors that can be tweaked before we let 5,000 lbs death machines roam around autonomously.