Almost all science fiction has some leap of imagination to make the story work. The Expanse tv show (and books) have the Epstein Drive and the protomolecule stuff. Obviously Star Trek is even more fantastical, so is Dune, or almost any space science fiction. Maybe Red Mars, Green Mars, Blue Mars is an exception (one has to assume fully terraforming Mars in a couple centuries is in fact doable), but there's no movie or tv show for those books.