For example, for $4k, you can get this with specs roughly equivalent to a normal developer machine: https://www.raptorcs.com/content/BK1SD1/intro.html
I bought two of these last year and they're great, stuff your own memory in there, add some storage and off you go.
Edit: clarified that this would be a mainboard + CPU.
[0] https://www.winehq.org/pipermail/wine-devel/2019-February/14...
For example, for $4k, you can get this with specs roughly equivalent to a normal developer machine: https://www.raptorcs.com/content/BK1SD1/intro.html