I'd imagine the generated code could be hardened similar to the code generated by clang ASAN, UBSAN and TSAN, and also wouldn't generate code that depends on undefined behaviour in the first place. Or you could do a little detour through WASM:

https://kripken.github.io/talks/2020/universal.html#/

In any case, that's better than shrugging off esoteric platforms, IMHO.