It's going to break all 3rd party social layer providers. Most news sites don't have native comments and rely on a 3rd party like a Disqus. Login in state is stored as a cookie. It also going to break all the openID stuff that is heavily used in organizations like Walmart. OpenID is all based around cookies. I remember having to rebuild our provider when Safari released an update that you can't set 3rd party cookies without user interaction.
That type of attitude toward the millions of users that use discus just shows why Firefox is a dying browser with ever decreasing install base. Funding will keep decreasing as it is tied to search engine deals which is based in active users.
Anything that shields me to some extent from the "grab money fast, before anyone notices we're fucking them over" companies out there is a champion, as far as I'm concerned.
there are valid criticisms of firefox but breaking disqus is a bizarre one. when is the last time you used it? my impressions is that these days the literal majority of content produced on it is spam and it's been this way for the better part of the last decade