These interim results are about as promising as you could expect, which is frankly amazing given it was developed in a matter of months (depending how you count, Moderna says "2 months"). Ultimately, its effectiveness depends on if and how quickly SARS-CoV-19 and its spike protein evolve resistance. That won't really be known until after widespread deployment and depends both on different factors inherent the virus' replication, its spike protein, host factors and how effectively the vaccine is rolled out.

Original article-- https://www.nejm.org/doi/full/10.1056/nejmoa2022483