Definitely not. I'm a passionate biohacker (normal people get shocked with how many different pills I self-prescribe) and trans admirer (yet I actually believe forcing people this way is an atrocity, they can only choose for themselves). What I actually hate, however, is political correctness (people who take "inappropriate" humor seriously and actually get or pretend offended - that's whom we should treat with hormones! ;-).
I’ll take your word for it. But I have certainly seen transitioning (which involves estrogen when the transition is mtf) referred to as biohacking in a way I don’t have to pretend to be offended by.