Here's what I wonder, and this is somewhat tangential to the issue-- the effects of cannabis are thought to be disruptive to some of the various stages of the sleep cycle, but at the same time, it can sure help you to achieve a full night of uninterrupted sleep. So in the context of these inflammation problems, I wonder what exactly it is about fitful sleep that leads to these inflammation responses and whether taking a toke before bed could be beneficial to your arteries.
Wishful thinking. You shouldn’t start with the substance you want to take and work backward to rationalize it.
There are plenty of milder, better-researched solutions suitable for longer term use without associated cognitive problems of cannabis. An extremely low dose of Trazodone, for example.
I would describe it more as taking the substance I've already decided to take regularly and speculating on the effects that it might have on various parts of my life. I certainly don't have fitful sleep anymore.