For me, real work means "realistically replace my laptop." The iPad cannot begin to do that. Apple could have designed IOS as a tightly integrated touch/keyboard-optional system, but they chose not to. Instead it's a bunch of app-centric silos that is decidedly hostile to most of my laptop-like keyboarding use cases.
Not irrelevant at all. The previous commenter's point was that many workflows have been made difficult/impossible by the design of the OS, and not for pro-user reasons. The iPad could support many additional uses cases without compromising at all on the ones it already serves. That is the frustration that is being expressed.