Given that these batteries would be used mostly in stationary applications, where space is less of a problem, the only question is how much extra power would the heaters and/or coolers need, and how much waste heat the charge/discharge releases (some of the waste heat could be used instead of the heaters, but would put more demand on the cooling system). Unless the amount of waste heat is too high, it doesn't sound like too much of problem to me; given proper insulation, most of the heat would come from the battery itself.
Cooling/heating Li-Ion batteries which have a wider range and are mechanically easier to cool than liquid Redox batteries is a big challenge, this one is a much bigger one.
