I'm 35, I've had issues with heartburn for most of my adult life. A few times, I've used baking soda temporarily when I don't have access to another antacid. I quit doing that, because of the last three times. The two times before last, my right knee dislocated ("popped out") hours after and I fell to the floor. That was startling. I didn't "correlate" that it could be related until the second time it happened. The final time I had it, I woke up to a burning and excruciating pain that coursed my entire back. I don't know if it was the ligaments, the discs, or what not but it was painful. I've felt that a few more times in the middle of the night without having had baking soda. So, very likely not related since it was a single dose. But, I'm not experimenting with baking soda as an antacid again with my knee having dislocated twice! There must be no relation but it's a lot like never eating a food again after getting terribly ill. Not gonna do that again!