He starts studying liquid fuel rockets in the '30s, and does some amazing work probably trailing only the top German engineers in this field.

He's denounced by some envious low-lifer who wanted his job and is arrested (along with Valentin Glushko, another great rocket scientist) during the stalinist Great Purge at the end of the '30s, when a simple anonymous note was enough to get someone disappeared. They torture him, sentence him to death - but then he's commuted to hard labor in the gold mine, where the poisonous environment and poor conditions meant the average life expectancy was barely over one year. Loses all his teeth to scurvy.

Meanwhile his friends back in Moscow are lobbying with Lavrenti Beria (the KGB boss) to release him - they succeed and he's placed in the "easy prison" where a bunch of intellectuals were doing essentially white collar slave labor (with pencil on paper, sure, but no choice in the nature of the work) for the Soviet government. He's released towards the end of WW2.

Then Stalin figures he needs to catch up to the Germans in rocketry, so Korolev is rehabilitated, made colonel of the Red Army, and finally starts working again on his rocket engines. They copy a bunch of German designs first, use some German engineers (who were prisoners) to get them started. Then continue on their own.

He develops the first Soviet ICBMs, but that was just what paid the bills. He keeps pushing for a real space program. Launches Sputnik 1 into space. Leads the Soviet space program until the mid-60s.

When he died, he was working on plans for manned missions to Mars and beyond.

I mean, what motivates a person to keep forging ahead against such adversity? Death sentence, hard labor in the poison mine, years of imprisonment and disgrace - and then he builds and launches the world's first ever satellite. To say nothing of the fact that, like Elon Musk, he was a man of many talents: great engineer, very effective leader, and a good politician and lobbyist. It's amazing.