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I would expect prions to be harder to sterilize than bacteria, actually. Prions aren't even alive.


They are much harder to sterilize, and autoclaves don't work. Ideally you'd dispose all tools exposed to prions, but if that's infeasible, the CDC recommends an autoclave in a bath of NaOH.

https://www.cdc.gov/prions/cjd/infection-control.html




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