I think what drives me nuts is that so often jQuery+Bootstrap would deliver a faster quicker product. While the big frameworks are incredible, they really are designed [1] for really large applications, ala Angular and Gmail. But, I see them being pushed onto what would otherwise be very simple projects: static websites, sites with a single contact form, etc.

1 - http://www.planningforaliens.com/blog/2016/04/11/why-js-deve...