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Aspera, is the current winner in Bioinformatics. The European Bioinformatics Institute and US NCBI are both big users of it. Mainly for INSDC (Genbank/ENA/DDBJ) and SRA (Short Read Achive) uploads.

For UniProt a smaller dataset we just use it to clone servers and data from Switzerland to the UK and US at 1GB/s over wide area internet.

Very fast, and quite affordable.



I used aspera for a while, but plain old HTTP over commodity networks works fine if you balance your transfers over many TCP connections.




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