Out of curiosity I'm curious why it scares you?

For context, I had been on Taltz before for psoriasis, and it worked very well. It seems like il17 inhibitors specifically are extremely targeted in what they affect.

In comparison, I was also on otezla at one point (tnf-a inhibitor) and it didnt work for me either, and the side effects were terrible.

It's the few instances of new onset IBD and generally the GI side effects. I'm lucky enough to have a pretty solid GI system that I don't want to risk messing with. I get very anxious with medicine, and my ankylosing spondylitis is sufficiently slow moving on MRI and tolerable enough that I prefer not to use the medicines. I had too many strange side effects whilst on Humira/Remicade such that it scares the crap out of me.

Understandable. I'll just say that for a sample size of n=1 I've seen no GI side effects with il17 blockers.

Which was not the case with otezla. But tnfa blockers - yeah those are bad times.

In any case, good luck with your treatment!

thank you and thanks for your n=1, wish you the best with your treatment as well

Wow, kid, you really have no clue about the world.